In-vitro fertilization (IVF) presents hope to couples facing the challenge of infertility; however, when in vitro fertilization is not successful after several attempts, the impact takes a heavy emotional, physical, and financial toll on the couple. Repeated IVF failure, which is generally described as an inability to have a clinical pregnancy after two or more IVF cycles with good-quality embryos, needs to be considered on a more detailed level and approached individually.

As the Best IVF Center in Indirapuram, we know what it is like to go through the heartbreak of a failed cycle, and we are determined to discover what is behind every case. In this blog, we shall discuss the reasons behind repeated IVF failure and the new treatment alternatives that can enhance your success in getting a successful pregnancy.

What Causes Repeated IVF Failure?

The first step in treating effectively is to ascertain the cause of failure. The usual reasons are:

1. Embryo Quality Issues

Other embryos might possess chromosomal abnormalities that do not allow implantation even with superior laboratory procedures.

2. Uterine Abnormalities

Such factors as fibroids, polyps, adhesions, or a thin endometrial lining may hinder an embryo's implantation.

3. Immunological Factors

The body may reject the embryo due to an overworking immune system that includes high levels of natural killer (NK) cells or autoimmune diseases.

4. Blood Clotting Disorders (Thrombophilia)

Blood flow to the uterus may be decreased by unrecognized clotting problems that can interfere with implantation and pregnancy.

5. Sperm DNA Fragmentation

High DNA fragmentation may affect the development of embryos, even in cases when the sperm count and motility seem to be normal.

6. Hormonal Imbalance or Poor Ovarian Response

The low quality of the egg or insufficient hormone level can lead to inadequate embryo development or uterine acceptability.

How Is Repeated IVF Failure Diagnosed?

We assess fertility comprehensively at Femmenest with the following:

• Embryo advanced genetic testing (PGT-A)

• To evaluate the uterus, 3D ultrasound and hysteroscopy are used.

• Endometrial Receptivity Analysis (ERA) to determine the best window of implantation

• NK cells immunological testing and autoimmune markers

• Sperm DNA fragmentation testing

• Hormonal assessments for thyroid, prolactin, and reproductive hormones

Each test is tailored based on your medical history and previous IVF cycles to ensure no potential cause is overlooked.

Treatment Options for Repeated IVF Failure

After knowing the cause, we have the best facility in Indirapuram, where our team provides high-level and individualized treatment to increase your chances of success:

1. Preimplantation Genetic Testing (PGT-A)

Before transfer, it is possible to test the embryo against chromosomal abnormalities, and the chances of miscarriage are significantly decreased, and chances of implantation are increased.

2. Endometrial Receptivity Testing (ERA)

The biopsy of the uterine endometrium defines the optimal time of embryo transfer and enhances the potential of implantation in women with a displaced window of implantation.

3. Hysteroscopic Correction of Uterine Abnormalities

Hysteroscopy can be used to remove polyps, fibroids, or adhesions and provide an ideal environment where an embryo can be implanted.

4. Immune Therapy

In the case of an autoimmune or inflammation disease, the immune response may be regulated with the help of medications such as steroids, intralipid infusion, or IVIG in case it is discovered.

5. Lifestyle and Nutritional Optimization

Egg and sperm quality and hormonal balance may be enhanced through nutritional counseling, weight management, and stress reduction.

Suggest to Read :- What Causes the Body to Reject an Embryo?

6. Donor Egg or Sperm Options

Donor gametes can be used as an alternative in the cases of exceptionally poor-quality eggs or sperm, which can significantly increase the results.

7. Surrogacy

When it happens that the environment of the uterus is not receptive, then gestational surrogacy becomes a safe and viable option for many couples.

Why Choose Femmenest – The Best IVF Center in Indirapuram?

At Femmenest, we care; we use technology and experience to make you beat recurrent IVF failures. This is what makes us different:

• Inclusion of a root-cause diagnosis-based personalized treatment approach

• Availability of high-technology reproductive techniques (ERA, PGT, ICSI, IMSI)

• An internal embryology and lab staff

• Emotional and psychological assistance at every phase

• Clear-cut treatment plans with high success rates

We do not only want a positive pregnancy test but a healthy, full-term baby.

Final Thoughts

The repetition of failed IVF is both arduous and emotional, but it does not mean the end. Many couples have successful pregnancies with proper diagnosis, expertise, and support, even after several attempts have failed.

We are also proud to be the best IVF center in Indirapuram at Femmenest, and we are here to guide you through every inch as you embark on a journey to parenthood.